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SBRT effective in men with metastasized prostate cancer


High-dose, targeted radiation can be a safe and effective option for men with oligometastatic prostate cancer, according to findings presented at the 61st Annual Meeting of the American Society for Radiation Oncology (ASTRO) in Chicago.

Results of the phase II trial determined that stereotactic ablative radiotherapy (SABR), also called stereotactic body radiation therapy (SBRT), could trigger an immune system response not thought possible in this type of cancer, said Phuoc Tran, MD, PhD, principal investigator of the trial. 

“This is the first bit of evidence that I’m aware of showing that SABR can induce a systemic immune response in patients with prostate cancer,” Tran, an associate professor of radiation oncology and molecular radiation sciences at the Johns Hopkins Kimmel Cancer Center, said in a prepared statement. “Other studies have made similar observations, but these are probably the most robust, sensitive and controlled observations that SABR can excite a systemic immune response.”

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