Home Colorectal Cancer MDS Patients Fare Worse With Two Mutated Copies of TP53 Than One,...

MDS Patients Fare Worse With Two Mutated Copies of TP53 Than One, Research Shows

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NEW YORK – It has long been established that mutations in TP53 — the gene most frequently altered across all cancer types — can be an important predictor of patients’ survival outcomes and response to treatment.

In myeloid dysplastic syndromes, for instance, TP53 mutations are associated with shorter overall survival, resistance to standard treatments, and the transformation of MDS into acute myeloid leukemia.

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https://www.precisiononcologynews.com/cancer/mds-patients-fare-worse-two-mutated-copies-tp53-one-research-shows

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