Home Depression Almond-rich, low carb diet can reduce depression risk in diabetics, says RCT

Almond-rich, low carb diet can reduce depression risk in diabetics, says RCT

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A bidirectional relationship has been found between T2DM and depression; depression increases the risk of the development of T2DM​ while T2DM increases the risk of depressio​n​. Therefore management of mental health is an important aspect of diabetes treatment. 

In China, a low-fat diet (LFD) is recommended for prevention and control of type 2 diabetes to help improve blood glucose levels. However, a meta-analysis​ has suggested a reasonable low-carb diet (LCD) is more beneficial for T2DM. Most studies support a protective effect of a low fat-high carb diet​ on depression but for T2DM patients carbohydrate is believed to be the greatest dietary contributor to blood glucose rise so it is important to explore what diet regimen is beneficial to both depression and glycometabolism.

Nuts, as part of LCD, have been shown to effectively improve glycosylated hemoglobin​ (HbA1c) levels and fasting blood glucoses (FBG) in T2DM patients. The almond is the most consumed and studied nut and its prebiotic properties​ have been shown to contribute to increased production of short-chain fatty acids (SCFAs) in the gut microbiome, which can promote the secretion of glucagon-like peptide 1 (GLP-1), an important regulator of microbiota–gut–brain signalling in health and stress-related psychiatric illnesses.

The current randomised controlled trial was carried out to compare the effects of an almond rich low carb diet (a-LCD) with a low-fat diet (LFD). This is one of only a few studies which have reported whether a diet regimen is beneficial to both depression and glycometabolism in T2DM patients. 

https://www.nutraingredients.com/Article/2020/10/06/Almond-rich-low-carb-diet-can-reduce-depression-risk-in-diabetics-says-RCT

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