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Sex not an independent risk factor for stroke mortality – Clinical Daily News

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Although several studies have suggested that women are disproportionately affected by stroke and may have poorer stroke outcomes, a new analysis shows no disparity in stroke outcomes base solely on sex.

Researchers at Geisinger analyzed electronic health record data for 8,900 patients who had an ischemic stroke between 2004 and 2019. Overall, female patients had a higher rate of all-cause mortality following stroke. After controlling for comorbidities such as atrial fibrillation, diabetes, heart failure and chronic lung or kidney diseases, however, survival rates for men and women were equal.

“Our study results indicate that women may have higher crude mortality after stroke; however, sex is not an independent risk factor for all-cause mortality in the rural communities that Geisinger serves,” said Vida Abedi, Ph.D., a scientist in the department of molecular and functional genomics at Geisinger and a co-author of the study. “Ischemic stroke recurrence and the composite outcome of stroke recurrence or death also did not demonstrate evidence of a sex disparity.”

Full results were published in Therapeutic Advances in Neurological Disorders.




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